Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle
نویسندگان
چکیده
منابع مشابه
Single muscle fiber proteomics reveals unexpected mitochondrial specialization
Mammalian skeletal muscles are composed of multinucleated cells termed slow or fast fibers according to their contractile and metabolic properties. Here, we developed a high-sensitivity workflow to characterize the proteome of single fibers. Analysis of segments of the same fiber by traditional and unbiased proteomics methods yielded the same subtype assignment. We discovered novel subtype-spec...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Medicine & Science in Sports
سال: 2015
ISSN: 0905-7188
DOI: 10.1111/sms.12606